Searchable abstracts of presentations at key conferences in endocrinology

ea0094op7.2 | RET and Endocrine Cancer | SFEBES2023

Peptide receptor radiotherapy (prrt) for well- differentiated metastatic paraganglioma and phaeochromocytomas (ppgl)

Frizelle Isolda , Velusamy Anand , McGowan Barbara , Breen Louise , Izatt Louise , Touska Philip , Christodoulou Dimitra , Eftychiou Nicolas , Hassan Fahim-ul , Carroll Paul

Introduction: Pheochromocytoma and Paraganglioma (PPGL) are neuroendocrine tumours arising from chromaffin cells in the adrenal medulla or ganglia in the autonomic nervous system. ~40% of PPGL arise due to germline mutation (commonly SDHx) and sporadic tumours frequently have causative somatic mutations. 15-20% of PPGL behave in a malignant manner. ~95% PPGL express somastostatin receptors and are GaDOTATATE avid. Lutathera® is a commercially available PR...